相關閱讀資料

老化之神經學、神經生理學、神經生物學

因舊版課程無指定課堂作業與考試，因此統整所有作業、講義、考試內容合併列出。

以下列出的是這門課程的閱讀列表。點擊其鏈結可以直接查看學術刊物論文的摘要。

The readings listed below provide the foundation of this course. Click on the links to view abstracts for the journal articles, where available.

閱讀列表

Reading List

Abrisquita-Gomez 等〈阿茲海莫症病人對情緒圖片的認知記憶〉《斯堪第那維亞神經醫學期刊》 105 (2002): 51-54.

Abrisquita-Gomez, et al."Recognition memory for emotional pictures in Alzheimer's patients." Acta Neurologica Scandinavica 105 (2002): 51-54.

Baddeley, A. D., S. Bressi, S. Della Sala, R. Logie, 與 H. Spinnler. 〈阿茲海莫症病人暫時認知記憶的下降〉《大腦雜誌》 114 (1991): 2521-2542.

Baddeley, A. D., S. Bressi, S. Della Sala, R. Logie, and H. Spinnler. "The decline of working memory in Alzheimer's disease." Brain 114 (1991): 2521-2542.

Baddeley, A. D. 〈暫時認知記憶〉《科學》 255 (1992): 556-559.

Baddeley, A. D. "Working memory." Science 255 (1992): 556-559.

Craik, F. I. M., 與 J. McDowd. 〈回憶與認知的年齡差距〉《實驗心理學雜誌學：學習記憶與認知》 13(3) (1987): 474-479.

Craik, F. I. M., and J. McDowd. "Age differences in recall and recognition." Journal of Experimental Psychology: Learning, Memory and Cognition 13(3) (1987): 474-479.

Glenner, G. G. 〈有關阿茲海莫症中類澱粉蛋白質以及其基礎〉《尖端臨床生物研究雜誌》. 317 (1989): 857-68.

Glenner, G. G. "Amyloid ® protein and the basis for Alzheimer's disease." Prog Clin Biol Res. 317 (1989): 857-68.

Glenner, G. G., 與 C. W. Wong. 〈阿茲海莫症與唐氏症：分享相同而獨一的腦血管類澱粉絲狀蛋白質〉《生物化學與生物物理研究交流雜誌》 122(3) (1984): 1131-5.

Glenner, G. G., and C. W. Wong. "Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein." Biochem Biophys Res Commun. 122(3) (1984): 1131-5.

Glisky, E.,等〈老年人的記憶來源：編碼的問題或是檢索的問題？〉《實驗心理學雜誌學：學習記憶與認知》 27(5) (2001): 1131-1146.

Glisky, E., et al. "Source memory in older adults: An encoding or retrieval problem?" Journal of Experimental Psychology: Learning, Memory and Cognition 27(5) (2001): 1131-1146.

Hamann,等〈阿茲海莫症病人恐懼能力的降低〉《神經心理學》 40 (2002): 1187-1195.

Hamann, et al. "Impaired fear conditioning in Alzheimer's disease." Neuropsychologia 40 (2002): 1187-1195.

Head, D., N. Raz, F. Gunning-Dizxon, A. Williamson, 與 J. D. Acker. 〈不同年齡的差異性中認知技巧取得的過程：大腦皮質萎縮以及認知能力的角色〉《心理與老年》 17 (2002): 72-84.

Head, D., N. Raz, F. Gunning-Dizxon, A. Williamson, and J. D. Acker. "Age-related differences in the course or cognitive skill acquisition: the role of regional cortical shrinkage and cognitive resources." Psychology and Aging 17 (2002): 72-84.

Irizarry, C., 與 B. Hyman. 〈阿茲海莫症治療〉《神經病理與實驗神經科學雜誌》 60(10) (2001): 923-928.

Irizarry, C., and B. Hyman. "Alzheimer disease therapeutics." Journal of Neuropathology and Experimental Neurology 60(10) (2001): 923-928.

Jonides, J., C. Marshuetz, E. E. Smith, E. E. Reuter-Lorenz, 與 A. Hartley. 〈不同年齡的行為差異性與正子掃描的干擾解析在語言暫時認知記憶中之不同〉《認知神經科學雜誌》 12 (2000): 188-196.

Jonides, J., C. Marshuetz, E. E. Smith, E. E. Reuter-Lorenz, and A. Hartley. "Age differences in behavior and PET activation reveal differences in interference resolution in verbal working memory." Journal of Cognitive Neuroscience 12 (2000): 188-196.

Kensinger, E., 與 S. Corkin. 〈老年的認知以及與認知有關之疾病節錄自〉《神經心理學百科全書》. 編輯者：G. Adelman. (in press).

Kensinger, E., and S. Corkin. "Cognition in aging and age-related disease." In Encyclopedia of Neuroscience. Edited by G. Adelman. (in press).

------. 〈阿茲海莫症〉節錄自《認知科學的百科全書》. 編輯者：L. Nadel. UK: Nature Publishing Group, 2003, 83-89.

------. "Alzheimer disease." In Encylcopedia of Cognitive Science. Edited by L. Nadel. UK: Nature Publishing Group, 2003, 83-89.

------. 〈老年的神經元改變〉節錄自《認知科學的百科全書》. 編輯者：L. Nadel. UK: Nature Publishing Group, 2003, 70-78.

------. "Neural changes in aging." In Encylcopedia of Cognitive Science. Edited by L. Nadel. UK: Nature Publishing Group, 2003, 70-78.

Kensinger, E. A., D. K. Shearer, J. J. Locascio, J. H. Growdon, 與 S. Corkin. 〈輕微阿茲海莫症與早期巴金森氏症之暫時認知記憶〉《神經心理學》 (in press).

Kensinger, E. A., D. K. Shearer, J. J. Locascio, J. H. Growdon, and S. Corkin. "Working memory in mild Alzheimer's disease and early Parkinson's disease." Neuropsychology. (in press).

Naveh-Benjamin, M. 〈成人記憶表現之年齡差異性：相關缺損研分析的試驗〉《實驗心理學雜誌學：學習記憶與認知》 26(5) (2000): 1170-1187.

Naveh-Benjamin, M. "Adult age differences in memory performance: Tests of an associative deficit analysis." Journal of Experimental Psychology: Learning, Memory and Cognition 26(5) (2000): 1170-1187.

Reuter-Lorenz, P. 〈老年人心智與大腦的新視野〉《認知神經科學趨勢》 6(9) (2002): 394-400.

Reuter-Lorenz, P. "New visions of the aging mind and brain." Trends in Cognitive Sciences 6(9) (2002): 394-400.

Rypma, B., V. Prabhakaran, J. E. Desmond, 與 J. D. Gabrieli. 〈前額葉活動在暫時認知記憶之年齡上的差異〉《心理學與老年》 16 (2001): 371-384.

Rypma, B., V. Prabhakaran, J. E. Desmond, and J. D. Gabrieli. "Age differences in prefrontal cortical activity in working memory." Psychology and Aging 16 (2001): 371-384.

Salthouse, T. 〈老年人的暫時認知記憶〉《神經病理學》 8 (1994): 535-543.

Salthouse, T. "The aging of working memory." Neuropsychology 8 (1994): 535-543.

Selkoe.〈第一部：原因與近期治療方向〉 545-552

Selkoe. "Part 1: Causes; Current Treatments." 545-552

Selkoe.〈第二部：s-分泌酶的抑制〉 552-556.

Selkoe. "Part 2: Inhibition of ß-Secretase." 552-556.

Selkoe, D. J., and D. Schenk. 〈阿茲海莫症：以分子生物學領域的了解預測以類澱粉胜肽為基礎的治療〉《藥理學與毒物學研究回顧雜誌》 43(2003): 545-84.

Selkoe, D. J., and D. Schenk. "Alzheimer's Disease: Molecular Understanding predicts Amyloid-based Therapeutics." Annu Rev Pharmacol Toxicol. 43(2003): 545-84.

Tessitore,等〈多巴胺調節對人類杏仁核的影響：有關巴金森氏症的研究〉《神經科學雜誌》 22(20) (1991): 9099-9103.

Tessitore, et al. "Dopamine modulates the response of the human amygdala: a study in Parkinson's disease." Journal of Neuroscience 22(20) (1991): 9099-9103.

請繳交一份下列文章的摘要：

Please present a Short Synopsis of:

Bard, F., C. Cannon, R. Barbour, R. L. Burke, D. Games, H. Grajeda, T. Guido, K. Hu, J. Huang,等〈利用週邊注入類澱粉胜肽抗體進入阿茲海莫症老鼠中樞神經系統以降低病理變化〉《自然醫學》 6(8) (2000): 916-9.

Bard, F., C. Cannon, R. Barbour, R. L. Burke, D. Games, H. Grajeda, T. Guido, K. Hu, J. Huang, et al. "Peripherally administered antibodies against amyloid ®-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease." Nat Med 6(8) (2000): 916-9.

Blanchard, B. J., A. E. Hiniker, C. C. Lu, Y. Margolin, A. S. Yu, 與 V. M. Ingram. 〈去除類澱粉胜肽之神經毒性〉《阿茲海莫症雜誌》. 2(2) (2000): 137-149.

Blanchard, B. J., A. E. Hiniker, C. C. Lu, Y. Margolin, A. S. Yu, and V. M. Ingram. "Elimination of Amyloid ® Neurotoxicity." J Alzheimers Dis. 2(2) (2000): 137-149.

Blanchard, B. J., G. Konopka, M. Russell, 與 V. M. Ingram. 〈與阿茲海莫症有關之類澱粉胜肽的機轉與神經毒性預防〉《腦部研究》. 776(1-2) (1997): 40-50.

Blanchard, B. J., G. Konopka, M. Russell, and V. M. Ingram. "Mechanism and prevention of neurotoxicity caused by ®-amyloid peptides: relation to Alzheimer's disease." Brain Res. 776(1-2) (1997): 40-50.

Citron, M., T. Oltersdorf, C. Haass, L. McConlogue, A. Y. Hung, P. Seubert, C. Vigo-Pelfrey, I. Lieberburg, 與 D. J. Selkoe. 〈類澱粉胜肽前驅蛋白質基因突變對阿茲海莫症病人類澱粉肽生成增加之影響〉《自然》 360(6405) (1992): 672-4.

Citron, M., T. Oltersdorf, C. Haass, L. McConlogue, A. Y. Hung, P. Seubert, C. Vigo-Pelfrey, I. Lieberburg, and D. J. Selkoe. "Mutation of the ®-amyloid precursor protein in familial Alzheimer's disease increases ®-protein production." Nature 360(6405) (1992): 672-4.

Hartley, D. M., D. M. Walsh, C. P. Ye, T. Diehl, S. Vasquez, P. M. Vassilev, D. B. Teplow, 與 D. J. Selkoe. 〈類澱粉胜肽的中間絲引起大腦皮質細胞急性電器生理變化進行性神經毒性〉《神經科學雜誌》 19(20) (1999): 8876-84.

Hartley, D. M., D. M. Walsh, C. P. Ye, T. Diehl, S. Vasquez, P. M. Vassilev, D. B. Teplow, and D. J. Selkoe. "Protofibrillar intermediates of amyloid ® -protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons." J Neurosci 19(20) (1999): 8876-84.

Morgan, D.,等〈在阿茲海莫症動物模型上試驗胜肽疫苗以避免記憶喪失〉《自然》 408(6815) (2000): 982-5.

Morgan, D., et al. "A ® peptide vaccination prevents memory loss in an animal model of Alzheimer's disease." Nature 408(6815) (2000): 982-5.

Schenk, D.,等〈利用免疫活化降低類澱粉胜肽之功能觀察在PDAPP老鼠之類阿茲海莫症病理變化〉《自然》 400(6740) (1999): 173-7.

Schenk, D., et al. "Immunization with amyloid-® attenuates Alzheimerdisease- like pathology in the PDAPP mouse." Nature 400(6740) (1999): 173-7.

Selkoe.〈第三部：c-分泌酶的抑制〉 556-564.

Selkoe.〈第四部：免疫方向對治療的想法〉 564-571.

Selkoe. "Part 4: Immunological Approach to Therapy." 564-571.

Selkoe.〈第五部：其他方向對治療的想法〉 571-576.

Selkoe. "Part 5: Other Approaches to Therapy." 571-576.

Sherrington, R., E. I. Rogaev, Y. Liang, E. A. Rogaeva, G. Levesque, M. Ikeda, H. Chi, C. Lin, G. Li, K. Holman,等〈複製一個突然變異基因於早發性家族性阿茲海莫症之研究〉《自然》 375(6534) (1995 ): 754-60.

Sherrington, R., E. I. Rogaev, Y. Liang, E. A. Rogaeva, G. Levesque, M. Ikeda, H. Chi, C. Lin, G. Li, K. Holman, et al. "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease." Nature 375(6534) (1995 ): 754-60.

Walsh, D. M., I. Klyubin, J. V. Fadeeva, W. K. Cullen, R. Anwyl, M. S. Wolfe, M. J. Rowan, 與 D. J. Selkoe. 〈自然分泌之類澱粉胜肽的寡分子抑制海馬迴細胞長期的活力之動物體內實驗〉《自然》 416(6880) (2002): 535-9.

Walsh, D. M., I. Klyubin, J. V. Fadeeva, W. K. Cullen, R. Anwyl, M. S. Wolfe, M. J. Rowan, and D. J. Selkoe. "Naturally secreted oligomers of amyloid ® protein potently inhibit hippocampal long-term potentiation in vivo." Nature 416(6880) (2002): 535-9.

Yan, R., P. Han, H. Miao, P. Greengard, 與 H. Xu. 〈阿茲海莫症分泌酶之穿膜主體決定晚期高基氏體位置以及類澱粉胜肽前驅蛋白質基質〉《生化學雜誌》. 276(39) (2001) : 36788-96.

Yan, R., P. Han, H. Miao, P. Greengard, and H. Xu. "The transmembrane domain of the Alzheimer's ®-secretase (BACE1) determines its late Golgi localization and access to ®-amyloid precursor protein (APP) substrate." J Biol Chem. 276(39) (2001) : 36788-96.