作業

突觸傳遞的生化學與藥理學

因舊版課程無指定課堂作業與考試,因此統整所有作業、講義、考試內容合併列出。

    作業是學期報告. 每位學生必須在學期中第四個星期結束前選擇一個作業裡的主題,然後在學期的第十三個星期前繳交報告。
    The assignment is a term paper. Students must choose a topic by end of fourth week of the term and submit their completed paper by thirteenth week of the term.  

     

    學期報告主題表
    List of Term Paper Topics 

     

    1. 原來很健康的22歲學生突然干擾上課的進行並且很明顯的開始產生幻覺。在所有的診斷中,她可能患有精神分裂症,或是狂躁症,或是藥物濫用。做為一個受過訓練的專業人士要如何分辨這些診斷?可用什麼樣的藥物治療,什麼樣的神經化學機制造成他們的行為?
    1. A previously healthy 22 year old suddenly disrupts classes and clearly starts hallucinating. She could be suffering from schizophrenia, or mania, or substance abuse - among other diagnoses. How might a trained professional distinguish among these possibilities? What drug treatments are available, and what neurochemical mechanisms probably underlie their actions?

    2.原來很健康的24歲學生開始表現出異常悲傷和異常憤怒之間輪替的情緒波動。有時他也會出現和週遭環境失去連結。他可能患有顳葉癲癇嗎?做為一個受過訓練的專業人士要如何決定?可用什麼樣的藥物治療,什麼樣的神經化學機制造成他們的行為?
    2. A previously healthy 24 year old student begins exhibiting mood swings that alternate between great sadness and great anger. He also sometimes appears to be unconnected to his environment. Might he have temporal lobe epilepsy? How might a trained professional decide? What drug treatments are available, and what neurochemical mechanisms probably underlie their actions?

    3.敘述恐慌發作,和思考可能構成它們的腦內機制。可用什麼樣的藥物治療,什麼樣的神經化學機制造成他們的行為?
    3. Describe panic attacks, and consider the brain mechanisms that might underlie them. What drug treatments are available, and what neurochemical mechanisms probably underlie their actions?

    4.壓力創傷後遺症是神經或是精神疾病 (或者都不是) ?可用什麼樣的藥物治療,什麼樣的神經化學機制造成他們的行為?
    4. Is post-traumatic stress disorder a neurologic or psychiatric disease (or perhaps neither)? What drug treatments are available, and what neurochemical mechanisms probably underlie their actions?

    5.敘述雙極化憂鬱症和現今治療背後的理論。
    5. Describe bipolar depression, and the theories that underlie its present treatment.

    6.做為一個受過訓練的專業人士要如何從主要憂鬱症的早期症狀來分辨和週遭環境事件有關的憂傷情緒?以及他/她可能如何處理這些情況?
    6. How might a trained professional differentiate sadness related to environmental events from early signs on major depressive disorders? And how would he/she probably treat these conditions?

    7.如何分辨早期的阿爾滋海默症和其它也可能造成老年人癡呆的神經和精神之疾病 (例如:憂鬱症,拳擊性痴呆症,血管性痴呆症,後天免疫症候群性癡呆症) ?可用什麼樣的藥物治療,和什麼樣的神經化學機制構成它們的行為?
    7. How might one differentiate early Alzheimer's Disease from other neurologic and psychiatric diseases that can also produce dementia in older people (e.g., depression, dementia pugilistica, vascular dementia, HIV dementia)? What drug treatments are available, and what neurochemical mechanisms probably underlie their actions?

    8.澱粉狀蛋白質是如何涉入蒙古症的形成和症狀?
    8. What is the involvement of amyloid in the course and symptoms of Downs' Syndrome?

    9.注意力缺乏症 - 過動症 - 是真的存在於兒童中及成人中?可用什麼樣的藥物治療,什麼樣的神經化學機制造成他們的行為?
    9. Is Attention Deficit Disorder - Hyperactivity - a real entity in children? In adults? What drug treatments are available, and what neurochemical mechanisms probably underlie their actions?

    10.敘述形成酒癮性痴呆症的神經化學和行為之過程。
    10. Describe the neurochemical and behavioral processes that are thought to underlie the development of alcoholic dementia.

    11.迷幻藥真的是神經毒嗎?
    11. Is Ecstasy really neurotoxic?

    12.對照古柯鹼戒斷症狀和鴉片戒斷症狀的徵兆和可能有關的機制。
    12. Contrast the signs of cocaine withdrawal and opiate withdrawal, and the probable mechanisms involved.

    13.敘述和對照現今藥物取得的方法和構成它們施用範圍的機制?
    13. Describe and contrast the currently available drug delivery methods and the mechanisms underlying the scope of their application.

    14.思考乙醯膽鹼在學習和記憶形成所扮演的腳色並將它運用在思考阿爾滋海默症和亨丁頓舞蹈症中所觀察到的不足。
    14. Consider the role of acetylcholine in learning and memory formation and relate it to the deficits observed in Alzheimer's and Huntington's disease.

    15.敘述中風後病人的麩胺酸毒害神經之機制和提出一個作為藥理學控制的目標。
    15. Describe the mechanism of glutamatergic neurotoxicity in post-stroke patients and propose a target for its pharmacological control.

    16.敘述在癲癇中伽馬安基丁酸能的神經傳遞質所扮演之角色特徵和提出一個藥理學的治療辦法。
    16. Characterize the role of GABAergic neurotransmission in epilepsy and propose a pharmacological means for its treatment.