相關閱讀資料、教學時程業、課堂講稿

遺傳神經生物學

因舊版課程無指定課堂作業與考試,因此統整所有作業、講義、考試內容合併列出。

    課程單元

    閱讀資料

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    1

    課程緒論

    Introduction to Course

     

     

    2

    細菌的化學感應

    Bacterial Chemoreception

     

    3

    學生簡報

    Student Presentations

    Berg,H.C.〈細菌的微處理〉《冷泉港定量生物學研討會》55(1990);539-45

    Berg, H. C. "Bacterial microprocessing." Cold Spring Harb Symp Quant Biol 55 (1990): 539-45.

     

    Adler,J.〈細菌的化學感受器〉《科學》166卷913期(196923月36日);1588-97

    Adler, J. "Chemoreceptors in bacteria." Science 166, no. 913 (December 26, 1969): 1588-97.

     

    Oosawa,K.,J.F.Hess和M.I.Simin.〈細菌趨化現象的突變缺陷顯示蛋白磷酸化的修飾〉《細胞》53卷1期(1988年4月8日),89-96

    Oosawa, K., J. F. Hess, and M. I. Simon. "Mutants defective in bacterial chemotaxis show modified protein phosphorylation." Cell 53, no. 1 (April 8, 1988): 89-96.

    4

    細菌和草履蟲的動力

    Bacterial and Paramecium Motility

    Zhang,Y.,H,Lu 和C.I.Bargmann.〈病原菌誘導Caenorthabditis綫蟲厭惡嗅覺的學習〉《自然》438卷7065期(2005年11月10日): 179-84

    Zhang, Y., H. Lu, and C. I. Bargmann. "Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans." Nature 438, no. 7065 (November 10, 2005): 179-84.

    5

    學生簡報

    Student Presentations

    Berg,H.C.〈細菌鞭毛的旋轉馬達〉《生物化學年度評論》72(2003);19-54,電子出版,2002年12月11日。

    Berg, H. C. "The rotary motor of bacterial flagella." Annu Rev Biochem 72 (2003): 19-54. Epub December 11, 2002.

     

    Blair,D.F.和H.C.Berg.〈有缺陷鞭毛馬達恢復扭距〉《科學》242卷4886期(1998,12,23);1678-81

    Blair, D. F., and H. C. Berg. "Restoration of torque in defective flagellar motors." Science 242, no. 4886 (December 23, 1988): 1678-81.

     

    Meister,M.,G.Glowe和 H.C.Berg.〈通過細菌鞭毛馬達的質子流量〉《細胞》49卷5期(1987年6月5日):643-50

    Meister, M., G. Glowe, and H. C. Berg. "The proton flux through the bacterial flagellar motor." Cell 49, no. 5 (June 5, 1987): 643-50.

    6

    神經基因組:基因組測序和神經系統

    Neurogenomics: Genome Sequencing and the Nervous System

    Carpenter,A.E. 和 D.M.Sabatini.〈全基因組範圍系統檢測基因功能〉《國家遺傳學評論》5卷1期(2004年1月):11-22

    Carpenter, A. E., and D. M. Sabatini. "Systematic genome-wide screens of gene function." Nat Rev Genet 5, no. 1 (January 2004): 11-22.

     

    Palladino,M.J.,L.P.Keegan,M.A.O’Connell和 R.A.Reenan.〈果蠅前體mRNA從A到I的剪輯主要參與成體神經系統的功能和整合〉《細胞》102卷4期(2000年8月18日):437-49

    Palladino, M. J., L. P. Keegan, M. A. O'Connell, and R. A. Reenan. "A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity." Cell 102, no. 4 (August 18, 2000): 437-49.

     

    Hoopengardner,B.,T.Bhalla,C.Staber和 R.Reenan.〈通過比較基因組鑒定神經系統中RNA剪輯的靶點〉《科學》301卷5634期(2003年8月8日):832-6

    Hoopengardner, B., T. Bhalla, C. Staber, and R. Reenan. "Nervous system targets of RNA editing identified by comparative genomics." Science 301, no. 5634 (August 8, 2003): 832-6.

    7

    學生簡報

    Student Presentations

     

    8

    神經系統的發育

    Development of the Nervous System

     

    9

    學生簡報

    Student Presentations

     

    10

    軸突導向的遺傳分析

    Genetic Analysis of Axonal Pathfinding

     

    學生簡報

    Student Presentations

     

    11

    膜興奮性的遺傳分析

    Genetic Analysis of Membrane Excitability

     

    學生簡報

    Student Presentations

     

    12

    小鼠的神經發育和功能

    Neurodevelopment and Function in the Mouse

    Kano,M.,K.Hashimoto,C.Chen,A.Abeliovich,A.Aiba,H.Kurihara,M.Watanabe,Y.Inoue和S.Tonegawa.〈PKC-γ突變鼠小腦發育過程中損傷突觸的消失〉《細胞》83 卷7 期(1995年12月29日):1223-31.

    Kano, M., K. Hashimoto, C. Chen, A. Abeliovich, A. Aiba, H. Kurihara, M. Watanabe, Y. Inoue, and S. Tonegawa. "Impaired synapse elimination during cerebellar development in PKC gamma mutant mice." Cell 83, no. 7 (December 29, 1995): 1223-31.

     

    Caviness,V.S.〈Reeler 突變小鼠:哺乳動物皮層發育過程中的遺傳實驗〉,《社會神經科學研討會》2(1977):27-46

    Caviness, V. S. "Reeler mutant mouse: a genetic experiment in developing mammalian cortex." Soc Neurosci Symp 2 (1977): 27-46.

    13

    學生簡報

    Student Presentations

     

    14

    神經終末處神經遞質的釋放

    Neurotransmitter Release at Nerve Terminals

     

    15

    學生簡報

    Student Presentations

     

    16

    感官知覺的遺傳分析

    Genetic Analysis of Sensory Perception

     

    17

    學生簡報

    Student Presentations

     

    18

    果蠅的高級腦功能:學習和晝夜節律

    Higher Brain Function in Drosophila: Learning and Circadian Rhythms

    Konopka,R.J. 和S.Benzer.〈果蠅melanogaster的時鐘突變〉《美國國家科學院院刊》68卷9 期(1971年9月):2112-6

    Konopka, R. J., and S. Benzer. "Clock mutants of Drosophila melanogaster." Proc Natl Acad Sci U.S.A. 68, no. 9 (September, 1971): 2112-6.

     

    Waddell,S.,J.D.Armstrong,T.Kitamoto,K.Kaiser和W.G.Quinn〈果蠅腦中兩個與記憶關係十分密切的神經元中表達健忘基因産物〉《細胞》103卷5期(2000年11月22日):805-13

    Waddell, S., J. D. Armstrong, T. Kitamoto, K. Kaiser, and W. G. Quinn. "The amnesiac gene product is expressed in two neurons in the Drosophila brain that are critical for memory." Cell 103, no. 5 (November 22, 2000): 805-13.

    19

    學生簡報

    Student Presentations

     

    20

    脊椎動物和無脊椎動物的突觸形成

    Synapse Formation in Vertebrates and Invertebrates

     

    學生簡報

    Student Presentations

     

    21

    小鼠學習和記憶的遺傳分析

    Genetic Analysis of Learning and Memory in Mice

     

    22

    學生簡報

    Student Presentations

    Nakazawa,K.,M.C.Quirk,R.A.Chitwood,M.Watanabe,M.F.Yeckel,L.D.Sun,A.Kato,C.A.Carr,D.Johnston,M.A.Wilson和S.Tonegawa.〈聯想回憶需要海馬CA3 NMDA受體〉《科學》297卷5579 期(2002年7月12日):211-8,電子出版 ,2002年5月30日

    Nakazawa, K., M. C. Quirk, R. A. Chitwood, M. Watanabe, M. F. Yeckel, L. D. Sun, A. Kato, C. A. Carr, D. Johnston, M. A. Wilson, and S. Tonegawa. "Requirement for hippocampal CA3 NMDA receptors in associative memory recall." Science 297, no. 5579 (July 12, 2002): 211-8. Epub May 30, 2002.

    23

    人類的神經遺傳學:記憶和疾病

    Neurogenetics in Humans: Memory and Disease

     

    24

    學生簡報

    Student Presentations

    Millar,J.K.,B.S.Pickard,S.Mackie,R.James,S.Christie,S.R.Buchanan,M.P.Malloy,J.E.Chubb,E.Huston,G.S.Bailie,P.A.Thomson,E.V.Hill,N.J.Brandon,J.C.Rain,L.M.Camargo,P.J.Whiting,M.D.Houslay,D.H.Blackwood,W.J.Muir和D.J.Porteous.〈精神分裂症中DISC1和PDE4B是調節cAMP信號的兩個相互作用的遺傳因子〉《科學》310卷5751 期(2005年11月18日):1187-91

    Millar, J. K., B. S. Pickard, S. Mackie, R. James, S. Christie, S. R. Buchanan, M. P. Malloy, J. E. Chubb, E. Huston, G. S. Baillie, P. A. Thomson, E. V. Hill, N. J. Brandon, J. C. Rain, L. M. Camargo, P. J. Whiting, M. D. Houslay, D. H. Blackwood, W. J. Muir, and D. J. Porteous. "DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling." Science 310, no. 5751 (November 18, 2005): 1187-91.