多尺度系統由具有兩個或多個長度尺度（奈米、微米、中尺度或巨觀尺度）的組件構成。在多尺度系統中，元件的工程建模、設計原理和製造過程完全不同。面臨的挑戰是建造這些元件並使它們和與之介面的其他尺度的元件在概念和模型上相容。這門課程涵蓋了尺度的基本性質、設計理論、建模方法和這些系統中需解決的製造問題。多尺度系統的例子包括精密儀器、奈米操縱器、纖維光學、微米/奈米光子學、奈米機器人學、微機電系統（壓電驅動操縱器和光學）、X光望遠鏡和碳奈米管配件。學生透過作業和一個工程文獻評論來掌握相關的資料。
Multi-scale systems (MuSS) consist of components from two or more length scales (nano, micro, meso, or macro-scales). In MuSS, the engineering modeling, design principles, and fabrication processes of the components are fundamentally different. The challenge is to make these components so they are conceptually and model-wise compatible with other-scale components with which they interface. This course covers the fundamental properties of scales, design theories, modeling methods and manufacturing issues which must be addressed in these systems. Examples of MuSS include precision instruments, nanomanipulators, fiber optics, micro/nano-photonics, nanorobotics, MEMS (piezoelectric driven manipulators and optics), X-Ray telescopes and carbon nano-tube assemblies. Students master the materials through problem sets and a project literature critique.
