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課 |
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課程單元 |
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閱讀資料 |
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1 |
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大腦行為研究之歷史及目標(1) |
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Mackay著,《決定論的瓦解─新科學家 第二期》,1970年,第26-26頁 [1] |
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2 |
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大腦行為研究之歷史及目標(2) |
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Rosenzweig著,《生物心理學 第一章:機會與展望》第1-21頁 {2, 3} |
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3 |
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大腦行為研究之歷史及目標(3) |
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Gazzaniga著,《認知神經科學的方法 第三章b節》,第75-120頁{3, 10-13, 20-38}
Gazzaniga著,《認知神經科學之簡史 第一章》第1-21頁 {3}
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4 |
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目標:當代理論及方法 |
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Rosenzweig著,《功能性神經解剖學 第二章》,第25-56頁 {4-5, 9-13}
Gazzaniga著,《認知的基層物質 第二章a節》第23-28頁 {4-5}
Gazzaniga著,《認知神經科學的方法 第三章a節》第69-74頁 {4-5}
Nauta 與 Feirtag著,《神經元 第二章;些許數目》第12-38頁 {4-6}
Nauta 與 Feirtag著,《解剖學上的區隔 第三章》第39-49頁 {4-5, 7-13}
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5 |
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神經細胞內之基礎細胞機制表現
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Rosenzweig著,《神經生理學 第三章:傳導、傳遞與神經訊號之整合》第55-85頁 {5-7}
Rosenzweig著,《分子生物學 附錄:基本概念與重要技巧》第A-1 到 A-8
Rosenzweig著,《精神病藥物學 第四章:神經傳導體、藥物與行為》第87-115頁 {5-7}
Rosenzweig著,《荷爾蒙與行為 第五章》第 117-146頁 {5, 11}
Gazzaniga著,《認知的基層物質 第二章b節》第28-44. {5-6}
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6 |
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神經內傳導及神經間傳遞 |
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Rosenzweig著,《感官處理與碰觸…等基本原則 第八章》第213-235頁 {6, 10-11} |
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7 |
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突觸傳遞(總結)與神經解剖學技術 |
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Rosenzweig著,《大腦的進化與行為 第六章》第149-175頁 {7-8}
Nauta與 Feirtag著,《早期的種系發展史 第一章;偉大的調節網絡》第1-11頁 {7-8}
Nauta 與 Feirtag著,《軸突的描繪 第四章》第50-61頁 {7}
*編者註:軸突(axon)乃為神經傳導的線路,負責將樹突(dendrite)接收刺激的訊號傳達到終端(terminal),終端則會將此神經細胞的刺激訊號傳達到下一個神經細胞。
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8 |
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*「中樞神經系統」及其演化之導論
*刺激─反應(Stimulation-Response)理論對比內生性之角色 |
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9 |
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*演化小語
*原始哺乳類腦部簡介
*反射及小腦路徑
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Nauta 與 Feirtag著,《第五章至第十章a節》第63-143頁 {9-14}
Gazzaniga著,《認知的基層物質 第二章c節》第44-68頁 {9-10}
Wolpert著,《演化 第十四章》第183-197頁 {9, 16}
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10 |
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*胚胎腦部次級細解
*傳導路徑:蹄系路徑
*橫斷效應與失聯絡現象的概念 |
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11 |
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*橫斷解剖、功能、物種差異
*新皮質、新蹄系及皮質脊髓路徑 |
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12 |
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*脊髓神經解剖
*自主神經系統
*奧圖羅威的發現 |
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13 |
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後腦及中腦描繪 |
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14 |
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中腦及前腦描繪 |
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15 |
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*神經解剖複習 *神經發展簡介 |
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Rosenzweig著,《大腦的壽命發展與行為 第七章》第177-210頁 {15-18}
Wolpert著,《外型的塑造 第二章》第11-28頁 {15-16}
Wolpert著,《形式的組成 第三章》,第31-58頁 {15-16}
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16 |
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*神經遷移介紹及種類
*各階段軸突之生長簡介 |
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Wolpert著,《幫大腦上發條 第八章》第119-133頁 {16-17}
Wolpert著,《發展的規劃 第十五章》第199-203頁 {16-17}
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17 |
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軸突生長:發展因素
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18 |
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*軸突生長之發展因素
*鄰近神經的側支及真實神經重生 |
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19 |
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運動系統(1):脊髓神經組織、退縮反射 |
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Bizzi, E等著,《青蛙的脊隨神經中運動行為的模件組織》,神經科學的潮流,第18期,1995年,第442-446頁 {19}
Rosenzweig著,《動態與行動(第一部份) 第十一章a節》第323-338頁 {19-20}
Gazzaniga著,《運動神經的控制 第十章》第371-421頁 {19-21}
Nauta 與 Feirtag著,《運動系統第七章a節:局部的運動器官》第91-94頁 {19-20}
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20 |
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運動系統(2):伸張反射、脊髓可塑性 |
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Rosenzweig著,《動態與行動(第二部份) 第十一章》第338-359頁 {20-21} |
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21 |
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*運動系統(3):下行路徑
*羅倫斯及古柏實驗(影片) |
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Klawans, Harold L著,《依然微笑(威爾森氏症) 第二章》,進一步的臨床神經學─牛頓的瘋狂,1990年,第19-29頁 {21}
Klawans, Harold L著,《蜥蝪(帕金氏症) 第五章》進一步的臨床神經學─牛頓的瘋狂,1990年,第53-65頁 {21}
Klawans, Harold L著,《危機下的主題(亨丁頓舞蹈症) 第十五章》,進一步的臨床神經學─牛頓的瘋狂,1990年,第140-150頁 {21}
Klawans, Harold L著,《她原本能夠徹夜跳著舞(亨丁頓舞蹈症) 第十六章》進一步的臨床神經學─牛頓的瘋狂,1990年,第151-157頁 {21}
Klawans, Harold L著,《雙眼飛舞的女孩(血清素引發的肌陣攣)第十八章》第165-173頁 {21}
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期中考 |
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22 |
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運動控制中之規律性輸出及時機 |
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Rosenzweig著,《振動的迴路….》第80-81頁,第346-349頁 {23}
Rosenzweig著,《生物的律動、睡眠與造夢 第十四章》第431-465頁 {23-24}
Rosenzweig、Dowling與John E著,《規律的運動行為之控制 第十章》神經元與神經網絡─神經科學之導論,哈佛大學出版社,1992年,第217-237頁 {23-24}
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23 |
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續:呼吸機制與活動/睡眠之律動
Activity and sleep rhythms |
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24 |
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內容為Wm Dement、安眠藥作用等等的「睡眠及清醒」影片欣賞 |
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25 |
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習慣與創新反應 |
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Rosenzweig著,《感官處理的一般原則 第八章a節》第213-235頁 (複習先前之閱讀) {26}
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26 |
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視覺系統(1):神經解剖、剝落效應 |
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Rosenzweig著,《視覺 第十章》 第281-321頁{26-30}
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27 |
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視覺系統(2):剝落效應 |
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Gazzaniga著,《認知與解碼 第四章》第121-161頁 {26, 29-33}
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28 |
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*視覺系統(3):剝落效應,為視網膜生理學做出結論 |
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29 |
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*視覺系統(4):視網膜、外側膝狀體、及其他(參照課文閱讀部分)
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Gazzaniga著,《更高級的感官功能 第五章》第163-205頁 {30-33} |
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30 |
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*視覺系統總結
*聽覺系統 |
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Rosenzweig著,《聽力,內耳感官….第九章》第247-269頁 {31-32} |
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31 |
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聽覺系統總結 |
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32 |
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疼痛及中腦中央灰質區 |
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Rosenzweig著,《觸覺與疼痛 第八章》 第213-245頁 {33}
講義:兩種激發系統 (邊緣系統與非邊緣系統) {33}
Rosenzweig著,《情感、積極與壓力 第十五章》第469-501頁 {33, 34-36}
Rosenzweig著,《嚐與聞 第九章》第269-279頁 {33}
Rosenzweig著,《性別 第十二章 第363-398頁》亦見第139-140頁{33-36}
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33 |
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下視丘與飲食 |
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Rosenzweig著《體內平衡 第十三章:內部狀態的積極管制》第399-432頁 {34-36} |
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34 |
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驅力對比回饋;競爭行為及神經倫理學 |
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35 |
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嶄新理論:生動機器人
人造情感的人格及行為選擇 |
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Rosenzweig著,《學習與記憶 第十七章:生物透視法》第537-570頁 {36-38}
Rosenzweig著,《學習與記憶 第十八章:神經機制》第571-605頁 {36-38}
Rosenzweig著,《語言與認知 第十九章》第607-642 {36-38}
Rosenzweig著,《事後:千變萬化的大腦》第643-651 {36-38}
Gazzaniga著,第7, 8, 9, 11章 {36-38}
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36 |
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較高層功能:人類本質和神經科學 |
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Rosenzweig著《精神病理學 第十六章:行為錯亂下的生物基礎》第503-534頁 {37-38} |
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37 |
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人類本質和神經科學,結論 |
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38 |
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複習、問答時間
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Rosenzweig著,《專業術語,G-1 到 G-26》(學生們必須在學期末前,了解絕大多數的詞彙) |
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期末考 |
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課 |
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課程單元 |
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閱讀資料 |
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1 |
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History and goals of brain-behavior studies, 1 |
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Mackay, "The bankruptcy of Determinism. New Scientist, 2", (1970), pp. 24-26. [1] |
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2 |
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History and goals, 2 |
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Rosenzweig, "ch. 1, Biological psychology: scope and outlook", pp. 1-21. {2, 3} |
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3 |
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History and goals, 3 |
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Gazzaniga, "ch. 3b, The methods of cognitive neuroscience", pp. 75-120. {3, 10-13, 20-38}
Gazzaniga, "ch. 1, A brief history of cognitive neuroscience", pp. 1-21. {3}
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4 |
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Goals: current theory and methods |
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Rosenzweig, "ch. 2, Functional neuroanatomy", pp. 25-56. {4-5, 9-13}
Gazzaniga, "ch. 2a, The substrates of cognition", pp. 23-28. {4-5}
Gazzaniga, "ch. 3a, The methods of cognitive neuroscience", pp. 69-74. {4-5}
Nauta & Feirtag, "ch. 2, The neuron; some numbers", pp. 12-38. {4-6}
Nauta & Feirtag, "ch. 3, Anatomical divisions", pp. 39-49.{4-5, 7-13}
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5 |
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Primitive cellular mechanisms
Expression in neurons
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Rosenzweig, "ch. 3, Neurophysiology: conduction, transmission, and integration of neural signals", pp.55-85. {5-7}
Rosenzweig, "Appendix. Molecular biology: basic concepts and important techniques", pp. A-1 to A-8.
Rosenzweig, "ch.4, Psychopharmacology: neurotransmitters, drugs, and behavior", pp.87-115. {5-7}
Rosenzweig, "ch. 5, Hormones and behavior", pp. 117-146. {5, 11}
Gazzaniga, "ch. 2b, The substrates of cognition", pp. 28-44. {5-6}
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6 |
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Neuronal conduction and transmission |
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Rosenzweig, "ch. 8, General principles of sensory processing, touch…", pp. 213-235. {6, 10-11} |
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7 |
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Transmission at synapses (concluded)
Neuroanatomical techniques |
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Rosenzweig, "ch. 6, Evolution of brain and behavior", pp. 149-175. {7-8}
Nauta & Feirtag, "ch. 1, Early phylogeny; the great intermediate net", pp. 1-11. {7-8}
Nauta & Feirtag, "ch. 4, Axon tracing", pp. 50-61. {7}
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8 |
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Intro to “CNS”and its evolution
S-R theory vs role of endogenous activity |
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9 |
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Notes on evolution
Primitive mammalian brain outline
Reflex and Cerebellar channels
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Nauta & Feirtag, "ch. 5-10a", pp. 63-143. {9-14}
Gazzaniga, "ch. 2c, The substrates of cognition", pp. 44-68. {9-10}
Wolpert, "ch. 14, Evolution", pp. 183-197. {9, 16}
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10 |
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Subdivisions of embryonic brain
Channels of conduction: lemniscal channels
Transection effects and diaschisis concept |
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11 |
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Transections, functions, species differences
Neocortex, neo-lemniscus, and corticospinal pathways |
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12 |
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Spinal cord anatomy
Autonomic N.S.
Otto Loewi’s discovery |
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13 |
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Hindbrain and midbrain pictures |
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14 |
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Midbrain and forebrain pictures |
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15 |
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Neuroanatomy review. Intro to development |
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Rosenzweig, "ch. 7, Life-span development of the brain and behavior", pp. 177-210. {15-18}
Wolpert, "ch. 2, Molding of form", pp. 11-28. {15-16}
Wolpert, "ch. 3, Pattern formation", pp. 31-58. {15-16}
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16 |
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Migration – types
Axon growth stages introduced |
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Wolpert, "ch. 8, Wiring the brain", pp. 119-133. {16-17}
Wolpert, "ch. 15, A programme for development", pp. 199-203. {16-17}
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17 |
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Axon growth: developmental factors
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18 |
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Developmental factors
Collateral sprouting and true regeneration |
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19 |
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Motor 1: spinal cord organization, withdrawal reflex |
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Bizzi, E. et al., "Modular organization of motor behavior in the frog’s spinal cord", Trends in Neuroscience, 18, (1995) pp.442-446. {19}
Rosenzweig, "ch 11a, Movements and actions (part 1)", pp. 323-338. {19-20}
Gazzaniga, "ch. 10, Motor control", pp. 371-421. {19-21}
Nauta & Feirtag, "ch. 7a, ... The motor system: Local motor apparatuses", pp. 91-94. {19-20}
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20 |
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Motor 2: stretch reflexes
Spinal plasticity |
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Rosenzweig, "ch. 11, Movements and actions (part 2)", pp.338-359. {20-21} |
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21 |
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Motor 3: descending pathways
Lawrence and Kuypers experiments (film) |
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Klawans, Harold L, "Ch.2, Still smiling (Wilson’s disease)", Newton’s madness, further tales of clinical neurology, (1990), pp. 19-29. {21}
Klawans, Harold L, "Ch. 5, The lizard (Parkinson’s disease)", Newton’s madness, further tales of clinical neurology, (1990), pp. 53-65. {21}
Klawans, Harold L, "Ch. 15, The subject at risk (Huntington’s chorea)", Newton’s madness, further tales of clinical neurology, (1990), pp. 140-150. {21}
Klawans, Harold L, "Ch. 16, She could have danced all night (Huntington’s chorea)", Newton’s madness, further tales of clinical neurology, (1990), pp. 151-157. {21}
Klawans, Harold L, "Ch. 18, The girl with dancing eyes (serotonin-induced myoclonus)", pp. 165-173. {21}
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MIDTERM EXAM |
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22 |
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Rhythmic output and timing in motor control |
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Rosenzweig, "Oscillatory circuits...", p. 80-81, pp. 346-349. {23}
Rosenzweig, "ch. 14, Biological rhythms, sleep, and dreaming", pp. 431-465. {23-24}
Rosenzweig, Dowling, John E., "ch. 10, Control of rhythmic motor behavior", Neuron and Networks, An Introduction to Neuroscience, Harvard Univ. Press, 1992, pp. 217-237. {23-24}
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23 |
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Continued: model of breathing mechanism
Activity and sleep rhythms |
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24 |
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Sleep and waking
Video showing Wm Dement, narcoleptics, etc. |
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25 |
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Habituation and novelty responses |
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Rosenzweig, "ch. 8a, General principles of sensory processing...", pp. 213-235 (review of previous reading). {26}
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26 |
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Visual system 1: neuroanatomy
Ablation effects |
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Rosenzweig, "ch.10, Vision...", pp. 281-321. {26-30}
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27 |
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Visual system 2: Ablation effects |
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Gazzaniga, "ch. 4, Perception and encoding", pp. 121-161. {26, 29-33}
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28 |
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Visual system 3: Ablations, concluded
Physiology of retina |
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29 |
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Visual system 4: Retina, LGB, and further (ref. to readings)
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Gazzaniga, "ch. 5, Higher perceptual functions", pp. 163-205. {30-33} |
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30 |
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Visual system, concluded
Auditory system |
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Rosenzweig, "ch. 9, Hearing, vestibular sensation...", pp. 247-269. {31-32} |
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31 |
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Audition concluded |
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32 |
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Pain and the midbrain central gray area |
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Rosenzweig, "ch. 8, ...Touch and pain", pp. 213-245. {33}
Handout: two arousal systems (limbic and non-limbic). {33}
Rosenzweig, "ch. 15, Emotions, aggression, and stress", pp. 469-501. {33, 34-36}
Rosenzweig, "ch. 9, ...Taste and smell", Page 4 of 5 pp. 269-279. {33}
Rosenzweig, "ch. 12, Sex, pp 363-398", also 139-140. {33-36}
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33 |
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Hypothalamus and feeding. |
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Rosenzweig, "ch. 13, Homeostasis: active regulation of internal states", pp 399-432. {34-36} |
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34 |
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Drive vs. reward; agonistic behavior and neuroethology |
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35 |
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New theory: animats
Affective synthetic characters and action selection |
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Rosenzweig, "ch. 17, Learning and memory: biological perspectives", pp. 537-570. {36-38}
Rosenzweig, "ch. 18, Learning and memory: neural mechanisms", pp. 571-605. {36-38}
Rosenzweig, "ch. 19, Language and cognition", pp. 607-642. {36-38}
Rosenzweig, "Afterward: The ever-changing brain", pp. 643-651. {36-38}
Gazzaniga, ch. 7, 8, 9, 11. {36-38}
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36 |
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Higher functions: human nature and neuroscience |
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Rosenzweig, "ch.16, Psychopathology: biological bases of behavior disorders", pp.503-534. {37-38} |
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37 |
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Human nature and neuroscience, conclusion |
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38 |
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Review
Question-and-answer sessions
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Rosenzweig: "Glossary, G-1 to G-26". (Students should know most of these terms by the end of the semester). |
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FINAL EXAM |
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