skip to content

» 麻省理工「開放式課程」首頁 » 生物學 » Foundations of Computational and Systems Biology, Spring 2004

教學時程

課	課程單元	重要日期
1	Introduction/Sequence Comparison and Dynamic Programming
2	Multiple Sequence Alignments I
3	Multiple Sequence Alignments II	Homework 1 handed out
4	Phylogenetic Analysis
5	Literature Discussion
6	Genome Sequencing and DNA Sequence Analysis	Homework 1 due
7	DNA Sequence Comparison and Alignment
8	DNA Motif Modeling and Discovery	Homework 2 handed out
9	Markov and Hidden Markov Models for DNA Sequences
10	DNA Sequence Evolution
11	RNA Secondary Structure Prediction	Homework 2 due
12	Literature Discussion on Predicting the Functions of DNA/RNA Sequences
13	Midterm Exam – in class – Protein and DNA Sequence Analysis
14	Protein Secondary Structure Prediction
15	Introduction to Protein Structure and Classification
16	Comparing Protein Structures Molecular Modeling: Methods and Applications
17	Using Computational Methods to Analyze, Predict, and Design Protein Sequences and Structures Solving Structures using X-ray Crystallographpy and NMR
18	Solving Structures using X-ray Crystallographpy and NMR (cont.) Homology Modeling	Homework 3 handed out
19	Methods for Protein Structure Prediction: Homology Modeling and Fold Recognition
20	Threading and ab initio Structure Prediction Computational Protein Design	Homework 3 due
21	Introduction to Systems Biology	Homework 4 handed out
22	Feedback Systems and Coupled Differential Equations
23	DNA Microarrays and Clustering
24	Literature Discussion on DNA Microarrays and Clustering	Homework 4 due (a day after Lec #24)
25	Computational Annotation of the Proteome
26	Literature Discussion on Computational Annotation of the Proteome