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1 |
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Bob Sauer |
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反應模式;簡單動力學及平衡
Reaction models; simple kinetics & equilibria |
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2 |
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動力學分析及平衡實驗
Analyzing kinetic & equilibria experiments |
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3 |
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自由能、熵、焓及循環
Free energy, entropy, enthalpy & cycles |
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4 |
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力、疏水性作用、螯合作用;
Forces, hydrophobic effect, chelate effect; |
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5 |
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分子結構及動態
Molecular structure and dynamics |
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6 |
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Tania Baker |
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蛋白質及核酸的物理性質
Physical properties of proteins and nucleic acids |
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7 |
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蛋白質純化之原理及實際應用
Principles and practice of protein purification |
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8 |
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(續上周)
(continued) |
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9 |
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考試一
EXAM 1 |
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10 |
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Tania Baker |
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區域及次單元組成; 分子量測定
Domain & subunit organization; molecular weight determination |
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11 |
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巨分子交互作用; 專一性、親和性及能量
Macromolecular interactions: specificity, affinity and energetics |
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12 |
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(續上周)
(continued) |
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13 |
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Frank Solomon |
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酵素催化: 動力學
Enzyme catalysis: kinetics |
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14 |
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酵素催化反應機制
Mechanism of enzyme catalyzed reactions: |
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15 |
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抑制劑及中間產物
inhibition and intermediates |
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16 |
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酵素催化反應機制: 化學
Mechanism of enzyme catalyzed reactions: chemistry |
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17 |
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酵素催化反應機制: 區隔化及交換
Mechanism of enzyme catalyzed reactions: partitioning & exchange |
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18 |
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酵素催化反應機制: 結合能
Mechanism of enzyme catalyzed reactions: binding energy |
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19 |
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催化專一性: 能量性及其他相關條件
Specificity of catalysis: energetics and consequences |
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20 |
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(續上周)
(continued) |
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21 |
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考試二
EXAM 2 |
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22 |
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Frank Solomon |
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雙向反應過程: 製造ATP
Coupled vectorial processes: making ATP |
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23 |
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雙向反應過程: 離子幫浦
Coupled vectorial processes: pumps |
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24 |
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雙向反應過程: 氧化磷酸化, 從形態學到酵素學
Coupled vectorial processes: OxPhos, morphology to enzymology |
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25 |
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雙向反應過程: 可反應性
Coupled vectorial processes: processivity |
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26 |
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雙向反應過程: 原動性; 聚合物-起源及構造和熱力學極性的後續發展
Coupled vectorial processes: Motors; Polymers – origins & consequences of structural & thermodynamic polarity |
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27 |
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雙向反應過程: 原動性; 構造和熱力學極性
Coupled vectorial processes: motors; structural & thermodynamic polarity |
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28 |
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雙向反應過程: 蛋白質摺疊
Coupled vectorial processes: protein folding |
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29 |
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複習
Review Session |
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30 |
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期末考
FINAL EXAM |
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