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| 1 |
緒論
Introduction |
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| 2 |
RNA干擾的發現
The Discovery of RNA Interference |
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| 3 |
RNAi的基本機制
The Basic Mechanism of RNAi |
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| 4 |
RNAi路徑之生理學關聯
Physiological Relevance of the RNAi Pathway |
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| 5 |
短干擾RNA(siRNA)和他們的細胞傳遞
Short-interfering RNAs (siRNAs) and their Delivery to Cells |
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| 6 |
siRNA的穩定表達：短髮卡式連接與表達載體
Stable Expression of siRNA: Short Hairpins and Expression Vectors |
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| 7 |
基因轉殖動物在自然條件下的關閉的傳代
Generation of Transgenic Animals for in vivo Silencing |
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| 8 |
鼠類基因轉殖研究所實地考察
Field Trip to Mouse-transgenesis Facility |
上交第一份課外作業
Assignment 1 due |
| 9 |
對第一份書面作業的討論
Discussion of First Written Assignment |
為第二份作業選擇一個期刊的文章
Choose journal article papers for second assignment |
| 10 |
siRNA有效序列的基因圖
Design of Potent siRNA Sequences |
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| 11 |
用RNAi進行大規模基因分析
Large-scale Genetic Analyses Using RNAi |
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| 12 |
學生對所選論文的口頭介紹
Student Oral Presentations of their Chosen Papers |
上交第二份課外作業
Assignment 2 due |
| 13 |
疾病防治中的RNAi使用
Using RNAi in the Prevention of Disease |
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| 14 |
課程總結和對RNAi未來的討論
Course Summary and Discussion on the Future of RNAi |
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