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| 1 |
Introduction (PDF) |
| 2 |
Discovery of the Ubiquitin Conjugation System (PDF) |
| 3 |
Protein Degradation in Trafficking Membranes I: Endoplasmic Reticulum Associated Degradation (ERAD) Pathway (PDF) |
| 4 |
Protein Degradation in Trafficking Membranes II: Endocytosis and lysosomal Degradation (PDF) |
| 5 |
Role of Ubiquitination in Transcriptional Regulation (PDF) |
| 6 |
Role of Ubiquitination in Cell Cycle Control and Programmed Cell Death (PDF) |
| 7 |
Ubiquitin-like Proteins (PDF) |
| 8 |
Functions of the Ubiquitin-Proteasome System in the Immune System (PDF) |
| 9 |
Ubiquitin and Cancer (PDF) |
| 10 |
Ubiquitin and Neurodegenerative Diseases: Alzheimer's and Parkinson's Diseases (PDF) |
| 11 |
More Diseases Involving Ubiquitin: Huntington's and Von Hippel-Lindau Disease (PDF) |
| 12 |
Too Much Degradation Can Be as Bad as Not Enough: Cystic Fibrosis and Liddle's Syndrome (PDF) |
| 13 |
Potential Therapeutic Strategies in Ubiquitin-Related Diseases (PDF) |
| 14 |
Oral Presentations
Final Comments and Course Evaluation |
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