|
|
|
|
|
» 首页 » Histology: Study of Cells, Tissues and Organs
|
|
|
 |
Objectives- To learn histology as it is a prelude and a prerequisite for the study of pathology.
- To learn the underlying fabric of form and function for all biological processes in health and in disease.
- To learn, develop, and hone listening and visual skills, problem solving and critical thinking skills, and construct and develop mental algorithms and tree structures-- important skills that are essential for all medical diagnoses.
- To learn the scaffolding of cells and tissues upon which to construct the principles of other basic sciences as well as many clinical sciences.
|
 |
1. Preface
The microscopic architecture and organization of cells,
tissues, and organs in relation to function is a central and fundamental
component in the study of Medicine. The rationale for studying this
organization is obvious, or will become so, and is based upon many factors.
However, the "Top Ten Reasons for Studying Histology" are as
follows.
- It is the prelude and absolute prerequisite
for the study of pathology. For medicine as well as medical
education it has been said that if the normal is learned so well and imprinted
into the brain, then the abnormal will be automatically recognized.
- It is the underlying fabric of form and function for all
biological processes in health and in disease. (We try to understand the
structure and function of our body's organ systems to achieve better
management of their clinical problems: Frost HM Anat Rec
262:398-419, 2001).
- It provides the scaffolding of cells and tissues upon which
to construct the principles of other basic sciences as well as many clinical
sciences, including biochemistry, physiology, immunology, hematology,
oral pathology......
- It is an excellent arena for honing skills in problem
solving and critical thinking.
- It is an ideal subject for learning to construct and develop
mental algorithms and tree structures-- important skills that are essential for
all medical diagnoses.
- It is an optimal medium for developing visual skills*. As
Yogi Berra has pointed out, "you can observe a lot just by
watching."
- It is a subject of images with great density. As a corollary
to number 6, these images can provide the observant viewer with a wealth of
information*. Indeed, "a picture IS worth a thousand
words."
- It can also be helpful for sharpening one's listening
skills. Despite any shortcomings its lecturers may exhibit,
histology can be likened to the "note" (pun intended) on
Wagner's music in Mark Twain's Autobiography (1924):
"[it's much] better than it sounds."
- It has often been said - perhaps since an early enunciation
by the Roman philosopher and statesman Lucius Annaeus Seneca (ca. 3-5BC-65AD) -
that "all art is but imitation of life". Much later, Oscar
Wilde offered the following: "All that I desire to point out is the
general principle that Life imitates Art far more than Art imitates
Life" (Intentions, 1891). Indeed, it is our
contentions that Life IS Art. In this regard, please consider
histology as a survey of some of the greatest architectural and
artistic masterpieces of the living form.*
- And finally, to paraphrase the distinguished
Spanish-American philosopher George Santayana (1863- 1952): Those who
cannot remember histology are condemned to repeat it (The Life of
Reason, Vol 1, 1905).
*In 2001, a former medical student, an art curator, and
a dermatology professor from Yale University School of Medicine published a
Letter to the Editor in the Journal of the American Medical Association, which
indicated that students' observational skills could be improved by at
least 10% when they participated in a course that examined and analyzed
preselected works of art (Dolev JC, Friedlaender LK, Braverman IM. Use of fine
art to enhance visual diagnostic skills. JAMA 256:1020, 2001).
The authors' contentions were as follows:
"Observational skills that define the astute clinician are usually only
acquired after years of clinical experience. Recognizing both the subtle and
obvious visual details is a critical aspect of visual diagnosis or "seeing."
Nonetheless, the formal teaching of observational skills is rarely included in
the medical curriculum." During the two-year study, 81 medical students
received visual training and 65 students served as a control group that
received no specific visual training. An important point made by the authors is
that one CAN be trained to be a better observer.
2. Readings
2.1. Required
- Ross et al. (2005) Histology. A Text and
Atlas. Lippincott Williams & Wilkins, Philadelphia.
- Avery (2002) Oral Development and Histology.
Thieme, New York. OR
- Berkovitz et al. (2002) Oral Anatomy, Histology
& Embryology. Mosby, Edinburgh.
-
Stedman's (2000) Medical
Dictionary. Lippincott Williams & Wilkins, Philadelphia.
OR
-
Dorland's (2003) Medical
Dictionary. Saunders, Philadelphia.
2.2. Recommended
- Avery (2000) Essentials of Oral Histology &
Embryology. Mosby, St. Louis.
- Gartner & Hiatt (2000) Color Atlas of
Histology (w/CD-ROM). LWW, Philadelphia.
- Kerr (1999) Atlas of Functional Histology.
Mosby, London.
- Young & Heath (2000) Wheater's Functional
Histology (w/CD-ROM). Churchill Livingstone, Edinburgh.
3. Schedule
| SCHEDULE |
|
Session -
Hours
|
Lecture/Lab Topic |
Lecturer |
Readings
(r=Ross a=Avery b=Berkovitz) |
| Cells &
Tissues |
|
1 - 4 hours |
Cells, Tissues & Organs: Methods of Study: Histochemistry;
Cells & Organelles |
Dr. Gustafson |
Ch. 1r, 2r |
|
2 - 3 hours |
Epithelium & Glands |
Dr. Gustafson |
Ch. 3r, 4r |
|
3 - 4 hours |
Epithelial Specializations |
Dr.
Gustafson |
Ch. 3r, 4r |
| Quiz #1 |
|
|
|
4 - 4 hours |
Blood |
Dr. Gustafson |
Ch.
9r |
|
5 - 3 hours |
Connective Tissue Proper |
Dr. Gustafson |
Ch. 5r, 6r |
|
6 - 4 hours |
Cartilage & Bone |
Dr. Gustafson |
Ch. 7r, 8r |
|
7 - 3 hours |
Osteogenesis |
Dr. Gustafson |
Ch. 8r |
| Quiz #2 |
|
|
|
8 - 4 hours |
Muscle |
Dr. Gustafson |
Ch.
10r |
|
9 - 4 hours |
Nervous Tissue |
Dr. Gustafson |
Ch. 11r |
| Organs &
Systems |
|
10 - 3 hours |
Organology |
Dr. Gustafson |
Ch. 10 (HistoNotes) |
| Review |
|
|
11 - 4 hours |
Examination 1 |
Staff |
|
|
12 - 4 hours |
Integument |
Dr. Marchant |
Ch.
14r |
|
13 - 3 hours |
Cardiovascular System |
Dr. Sonnenschein |
Ch. 12r |
|
14 - 4 hours |
Alimentary System: Oral Cavity Overview; Oral Mucosa |
Dr. Gustafson |
Ch. 14ab, 15a |
|
15 - 4 hours |
Alimentary System: Oral Cavity Salivary Glands |
Dr. Gustafson |
Ch. 17a, 16b |
| Quiz #3 |
|
|
|
16 - 3 hours |
Alimentary System: Oral Cavity Odontogenesis |
Dr. Marchant |
Ch. 5a, 6a, 21ffb |
|
17 - 4 hours |
Alimentary System: Oral Cavity Eruption & Shedding |
Dr. Nurminsky |
Ch. 7a, 26b |
|
18 - 4 hours |
Alimentary System: Oral Cavity Enamel |
Dr.
Marchant |
Ch. 9a, 7b |
|
19 - 3 hours |
Alimentary System: Oral Cavity Dentin/Pulp |
Dr.
Giunta |
Ch. 10a, 11a, 9b, 10b |
|
20 - 2 hours |
Alimentary System: Oral Cavity Cementun/Periodontium |
Dr. Giunta |
Ch. 13a, 15a, 11b,
12b |
| Quiz #4 |
|
|
|
20 - 2 hours |
Temporomandibular Joint
|
Dr.
Mehta |
20a, 15b |
|
21 - 3 hours |
Review |
TBA |
|
|
22 - 4 hours |
Examination II |
Staff |
|
|
23 - 3 hours |
Lymphoid (Immune) System I |
Dr. Marchant |
Ch. 13r |
|
24 - 4 hours |
Lymphoid (Immune) System II |
Dr.
Marchant |
Ch. 13r |
|
25 - 4 hours |
Alimentary System: Esophagus & Stomach |
Dr.
Gustafson |
Ch. 16r |
|
26 - 3 hours |
Alimentary System: Intestines |
Dr.
Gustafson |
Ch. 16r |
|
27 - 4 hours |
Alimentary System: Liver, GB & Pancreas |
Dr.
Gustafson |
Ch. 17r |
| Quiz #5 |
|
|
|
28 - 4 hours |
Respiratory System |
Dr. Marchant |
Ch. 18r |
|
29 - 3 hours |
Urinary System |
Dr. Nurminsky |
Ch. 19r |
|
30 - 4 hours |
Review |
Dr. Gustafson |
|
|
31 - 4 hours |
Examination III |
Staff |
|
|
32 - 3 hours |
Endocrine Glands I |
Dr. Soto |
Ch. 20r |
|
33 - 4 hours |
Endocrine Glands II |
Dr. Soto |
Ch. 20r |
|
34 - 4 hours |
Genital System: Male |
Dr. Gustafson |
Ch. 22r |
| Quiz #6 |
|
|
|
35 - 3 hours |
Genital System: Female |
Dr. Soto |
Ch. 21r |
|
36 - 3 hours |
Examination IV |
Staff |
|
4. Course Faculty
4.1. Course Director
- Dr. Alvar W. Gustafson, PhD, Department of Anatomy & Cellular Biology
4.2. Teaching Faculty: Instructors & Lecturers
- Dr. John Giunta, DMD, Department of Oral Pathology; emeritus
- Dr. Jeff Marchant, PhD, Department of Anatomy & Cellular Biology
- Dr. Noshir Mehta, DMD, Department of General Dentistry
- Dr. Maria Nourminskaia, PhD, Department of Anatomy & Cellular Biology
- Dr. Dmitry Nurminsky, PhD, Department of Anatomy & Cellular Biology
- Dr. Carlos Sonnenschein, MD, Department of Anatomy & Cellular Biology
- Dr. Ana Soto, MD, Department of Anatomy & Cellular Biology
- Dr. Frank R. Susi, DMD, PhD, Tufts University School of Dental Medicine, emeritus
5. Examinations and Quizzes
5.1. Coverage and Weight of Examinations
-
Examination I: Methods/Histochemistry -
Nervous Tissue (50 pts)
-
Examination II: Organology - TMJ (55 pts)
-
Examination III: Immune System - Urinary
System (35 pts)
-
Examination IV: Endocrine Glands -
Genital Systems (30 pts)
5.2. Coverage and Weight of Quizzes
-
Quiz #1: Methods of Study/Histochemistry
- Epithelium & Glands (6 pts)
-
Quiz #2: Epithelial Specializations -
Cartilage & Bone (6 pts)
-
Quiz #3: Integument - Oral Mucosa (6 pts)
-
Quiz #4: Salivary Glands - Dentin/Pulp (6
pts)
-
Quiz #5: Lymphoid (Immune) System -
Intestines (6 pts)
-
Quiz #6: Endocrine Glands (6
pts)
|
|