本课程介绍可于分子层级来了解细胞的基本计算机计算原理。包含了序列排比算法、动态规划、杂凑表、字尾树、以及Gibbs取样等主题。此外，本课程亦着重于计算方法如：基因与其物理位置之对映；基因体定序、重组及注解；RNA表现与二级结构；蛋白质结构与折叠；以及分子间的交互作用与动力学。
This course introduces the basic computational methods used to understand the cell on a molecular level. It covers subjects such as the sequence alignment algorithms: dynamic programming, hashing, suffix trees, and Gibbs sampling. Furthermore, it focuses on computational approaches to: genetic and physical mapping; genome sequencing, assembly, and annotation; RNA expression and secondary structure; protein structure and folding; and molecular interactions and dynamics.
