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本课程的教材专注在于生物物理、生物化学、以及与生理学有关的药物作用、交互作用、分布、代谢与毒性的基本原理。本课程包括了课堂讲习，麻州综合医院实习示范一节，以及讲师或学生主导的个案研讨 。
评分
H选读HST(卫生科学与科技)这堂课的学生将被评鉴为杰出、满意或是不满意。对于近乎满意的案例亦可给予近乎满意的评鉴卫生科学与科技(或 HMS哈佛医学院) 硕士生的成绩则将记录为及格与不及格。这些评鉴将根据学生的书面作业、课堂作业与口述(头)报告，再加上期中考与期末考。
教科书
指定
Katzung, B. ed. . 《基础与临床药理》(Basic and Clinical Pharmacology) 第八版，纽约麦格罗．希尔出版社，2001年。
非指定
Hardman, J. G. ed. 《治疗的药理学基础》(The Pharmacological Basis of Therapeutic)第十版，纽约麦格罗．希尔出版社，2001年。
《G&G》 (出自原始编辑的姓名缩写Goodman and Gilman) 是一本很棒的参考书。你们当中许多人会想要在书架上摆一本 。新的版本大约每五年发行一次
The course material will focus on the basic principles of biophysics, biochemistry and physiology related to drug action and interaction, distribution, metabolism and toxicity. The course will consist of lectures, a clinical demonstration session at Massachusetts General Hospital, and lecturer- and student-led case discussions.
Grading
HST students taking this course will be graded on an Excellent, Satisfactory, Unsatisfactory basis. The grade of Marginally Satisfactory may also be given in borderline cases. HST (or HMS) M.D. student grades will be recoded as Pass/Fail. Student evaluations will be based on written homework, classroom work and oral presentations, as well as the midterm and final examinations.
Texts
Required
Katzung, B. ed. Basic and Clinical Pharmacology. 8th ed. New York: McGraw-Hill, 2001.
Optional
Hardman, J. G. ed. The Pharmacological Basis of Therapeutics. 10th ed. New York: McGraw-Hill, 2001.
"G&G" (named for the original editors, Goodman and Gilman) is an excellent reference many of you will want on your shelves. New editions have been coming out at roughly five year intervals.
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