相关阅读资料部分列出了本课程全面的参考书目。

A full bibliography is included in the readings section of this course.

本课程为麻省理工学院生物系提供的 本科高级研讨讲座之一。这些研讨讲座的互动性很强，是专为对利用原始研究文献来探讨学习当前生物学相关研究感兴趣的学生而设的，其许多教师都是对教学有着浓厚兴趣的博士后。本门课程教师――Halme博士，为HHMI Education Group(Howard Hughes医学研究会)教育团体成员。

This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. The instructor for this course, Dr. Halme, is a member of the HHMI Education Group.

每次感染都是一次侵染病原体与被侵染宿主间的战斗。病原体必须逃过宿主免疫系统的重重防御，直至能够在宿主细胞内复制及扩散到其它细胞中，才算侵染成功。在侵染过程中，病原体必须逃避宿主三大免疫功能之一：检测、激活及效应功能。本课程将讨论疾病特异性的免疫逃逸例子，及在这些例子中病原体战胜宿主免疫系统的机制。同时探讨的还有这些宿主――病原体间相互作用所揭示的免疫系统的正常功能和基本的细胞生物学过程，如蛋白质的成熟和降解。

Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation.