| 课 |
课程单元 |
重点日期 |
| 1 |
基因的实体结构
Physical Structure of the Gene |
|
| 2 |
互补试验(顺反测试)与基因的功能
The Complementation Test & Gene Function |
|
| 3 |
孟德尔遗传学
Mendelian Genetics |
|
| 4 |
机率与谱系
Probability and Pedigrees |
|
| 5 |
染色体与性联遗传
Chromosomes and Sex Linkage |
|
| 6 |
重组与基因图谱
Recombination and Genetic Maps |
习题 1 缴交
PS 1 due |
| 7 |
三基因相交 (三点杂交)
Three-factor Crosses |
|
| 8 |
四分体分析
Tetrad Analysis |
|
| 9 |
噬菌体遗传学
Phage Genetics |
习题 2 缴交
PS 2 due |
| 10 |
基因结构与DNA分析
Gene Structure and DNA Analysis |
|
| 11 |
突变与抑制子
Mutations and Suppressors |
|
| |
1-10 讲
Lectures 1-10 |
第一次期中考
EXAM I |
| 12 |
细菌遗传学: 转位
Bacterial Genetics: Transposition |
|
| 13 |
细菌遗传学: 转导
Bacterial Genetics: Transduction |
|
| 14 |
细菌的互补作用: 质体
Complementation in Bacteria: Plasmids |
|
| 15 |
细菌的互补作用: DNA重组
Complementation in Bacteria: Rec. DNA |
|
| 16 |
原核生物的调控: 负向控制
Prokaryotic Regulation: Negative control |
习题 3 缴交
PS 3 due |
| 17 |
原核生物的调控: 正向控制
Prokaryotic Regulation: Positive control |
|
| 18 |
原核生物的调控: 网状调控
Prokaryotic Regulation: Regulatory circuits |
|
| 19 |
原核生物的调控: 融合操纵子
Prokaryotic Regulation: Operon fusions |
习题 4 缴交
PS 4 due |
| 20 |
真核基因的调控 I
Eukaryotic Gene Regulation I |
|
| 21 |
真核基因的调控 II
Eukaryotic Gene Regulation II |
|
| |
11-19 讲
Lectures 11-19 |
第二次期中考
EXAM II |
| 22 |
真核基因与基因组
Eukaryotic Genes and Genomes |
|
| 23 |
在老鼠中的基因转殖&基因标定 I
Transgenes & Gene Targeting in Mice I |
|
| 24 |
在老鼠中的基因转殖&基因标定 II
Transgenes & Gene Targeting in Mice II |
|
| 25 |
族群遗传学:Hardy-Weinberg 哈代-温博格(定律)
Population Genetics: Hardy-Weinberg |
|
| 26 |
族群遗传学:突变 & 筛选
Population Genetics: Mutation & Selection |
习题 5 缴交
PS 5 due |
| 27 |
族群遗传学: 近交(自交)
Population Genetics: Inbreeding |
|
| 28 |
人类的多型性
Human Polymorphisms |
|
| 29 |
联会的统计评量I
Statistical Evaluation of Linkage I |
|
| 30 |
联会的统计评量II
Statistical Evaluation of Linkage II |
习题 6 缴交
PS 6 due |
| 31 |
复杂性状
Complex Traits |
|
|
20-30 讲
Lectures 20-30 |
第三次期中考
EXAM III |
| 32 |
染色体的异常与染色体的不分离 I
Chromosome Anomalies & Nondisjunction I |
|
| 33 |
染色体的异常与染色体的不分离 II
Chromosome Anomalies & Nondisjunction II |
习题 7 缴交
PS 7 due |
| 34 |
人类性别的决定
Human Sex Determination |
|
| 35 |
癌症遗传学 I
Genetics of Cancer I |
|
| 36 |
癌症遗传学 II
Genetics of Cancer II |
|
