以下表格提供课程讲授(L)及考试(E)资讯The table below provides information on the course's lecture (L) and exam (E) sessions.
教科书:Text Readings
所有课程内容都在Dill, K. 及S. Bromberg的《分子级驱动力》一书中(New York: Garland Press, 2003. ISBN: 0815320515.)All Text Readings are in Dill, K., and S. Bromberg. Molecular Driving Forces. New York: Garland Press, 2003. ISBN: 0815320515.
额外参考资料:Additional References
van Holde, K. E., W. C. Johnson及P. S. Ho共同著作之《物理生物化学原理》 Upper Saddle River, NJ: Prentice Hall, 1998. ISBN: 0137204590.van Holde = van Holde, K. E., W. C. Johnson, and P. S. Ho. Principles of Physical Biochemistry. Upper Saddle River, NJ: Prentice Hall, 1998. ISBN: 0137204590.
Eisenberg, D.,及D. Crothers共同著作之《应用于生命科学的物理化学》 Menlo Park, CA: Benjamin/Cummings, 1979. ISBN: 080532402X.Eisenberg = Eisenberg, D., and D. Crothers. Physical Chemistry with Applications to the Life Sciences. Menlo Park, CA: Benjamin/Cummings, 1979. ISBN: 080532402X.
Kittel, C.及 H. Kroemer共同著作之《热物理》第二版 San Francisco CA: W. H. Freeman, 1980. ISBN: 0716710889Kittel = Kittel, C., and H. Kroemer. Thermal Physics. 2nd ed. San Francisco CA: W. H. Freeman, 1980. ISBN: 0716710889.
| L1 |
简介Introduction
统计力学的目的Purpose of Stat Mech
机率Probability |
Ch. 1 (Ex. 1.1-1.6) |
|
| L2 |
机率Probability |
Ch. 1, 2 |
|
| L3 |
平衡状态Equilibrium States |
Ch. 2 (Through Ex. 2.2) |
|
| L4 |
平衡状态– 扩散之晶格模型Equilibrium States – Lattice Model for Diffusion
橡胶弹性学Rubber Elasticity |
Ch. 2 |
|
| L5 |
简介热力学守恒定律(第一定律,量化与第二定律)Introduction to Conservation Laws (1st Law, Quantization, 2nd Law) |
Ch. 3 |
|
| L6 |
外延性质:波兹曼定律与熵(entropy)Boltzmann's Law and Entropy as an Extensive Property
“熵”(entropy)增加的定律Law of Increased Entropy |
Ch. 6 (Through Ex. 6.2) |
Kittel, Ch. 2 |
| L7 |
波兹曼定律与外延性质熵(entropy)More Boltzmann's Law
分配函数Partition Functions |
Ch. 6 |
|
| L8 |
模拟计算Simulations
聚合酵素链锁反应PCR |
|
|
| E1 |
随堂测验一Quiz I |
|
|
| L9 |
热力学系统Thermodynamic Systems
内含与外延性质Intensive/Extensive Properties
能量与熵(Entropy)的基本方程式Fundamental Equations for Energy and Entropy
热力学驱动力之定义(第一部分)热力学作用力Definitions of Thermodynamic Driving Forces (Part 1) Thermodynamic Forces
齐次函数Homogeneous Functions
平衡,温度与压力的定Definition of Equilibrium, Temperature, Pressure |
Ch. 7 (To Ex. 7.4) |
|
| L10 |
简介化学位能-热循环-热,功与能量之间关系的第一定律Introduction to Chemical Potential - Thermo Cycles - First Law Relations between Heat, Work, Energy |
Ch. 7 |
|
| L11 |
可逆与不可逆程序Reversible and Irreversible Processes |
Ch. 7 |
|
| L12 |
简介自由能Introduction to Free Energy
赫姆荷兹自由能Helmholtz Free energy |
Ch. 8 |
|
| L13 |
焓Enthalpy
吉布斯自由能Gibbs Free Energy |
Ch. 8 |
Kittel Problem, 9.4
van Holde, Ch. 2 |
| L14 |
基本方程式与其自然变数Fundamental Equations and their Natural Variables
热容 Heat Capacities
平衡温度Equilibrium Temperature |
Ch. 8 |
|
| L15 |
热力学循环Thermodynamic Cycles
卡若循环与不等性质Carnot Cycle and Inequality
热引擎Heat Engines
路径相依性Path Dependence |
Ch. 8 |
Kittel, Ch. 8 |
| L16 |
莫尔偏微性质Partial Molar Properties |
Ch. 9 |
|
| L17 |
莫尔偏微性质IIPartial Molar Properties II |
Ch. 9 |
Eisenberg, Ch. 7 |
| L18 |
计算机模拟Simulations
蒙地卡罗法Monte Carlo |
|
|
| E2 |
随堂测验二 Quiz II |
|
|
| L19 |
波兹曼分布定律Boltzmann Distribution Law |
Ch. 10 |
|
| L20 |
分配函数Partition Functions |
Ch. 10 |
|
| L21 |
从分配函数预测热力学性质Prediction of Thermodynamic Properties from Partition Functions
系集Ensembles |
Ch. 10 |
Eisenberg, Ch. 14 |
| L22 |
量子分布函数Quantum Partition Function |
Ch. 10, 11 |
|
| L23 |
均分原理Equipartition |
Ch. 11 |
|
| L24 |
均分原理 (续)Equipartition (cont.) |
Ch. 11 |
|
| L25 |
化学平衡Chemical Equlibria
列沙特勒原理 (Ex. 8, 蛋白质的应力变性)Le Chatelier's Principle (Ex. 8, Pressure Denaturation of Proteins)
凡特何夫(van’t Hoff)原理van't Hoff |
Ch. 13 (To Ex. 13.18) |
van Holde, Ch. 3 |
| L26 |
固-液-气平衡Solid-liquid-gas Equilibrium |
Ch. 14 |
|
| L27 |
溶液与混合物Solutions and Mixtures
高分子Polymers |
Ch. 15, 31 |
|
| L28 |
溶解现象:渗透压Solvation – Osmotic Pressure |
Ch. 16 |
|
| L29 |
溶解现象:蛋白质/巨分子在介面的吸附现象Solvation – Protein/Macromolecule Adsorption at Interfaces |
Ch. 16 |
van Holde, Ch. 2 |
| L30 |
高分子链Polymer Chain |
Ch. 31 |
|
| E3 |
随堂测验三Quiz III |
|
|
| L31 |
高分子链 IIPolymer Chain II |
Ch. 32 |
|
| L32 |
高分子链 IIIPolymer Chain III |
Ch. 33 |
|
| L33 |
协同性Cooperativity |
Ch. 26 |
|
| L34 |
协同性 (续) Cooperativity (cont.) |
Ch. 28 |
|
| L35 |
蛋白质摺叠现象Protein Folding |
|
van Holde, Ch. 2 |
| L36 |
回顾Review |
|
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