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审定:蔡瑞莹(简介并寄信)
翻译:谢明发(简介并寄信)
编辑:朱学恒(简介并寄信)

以下表格提供课程讲授(L)及考试(E)资讯
The table below provides information on the course's lecture (L) and exam (E) sessions.

教科书:
Text Readings

所有课程内容都在Dill, K. 及S. Bromberg的《分子级驱动力》一书中(New York: Garland Press, 2003. ISBN: 0815320515.)
All Text Readings are in Dill, K., and S. Bromberg. Molecular Driving Forces. New York: Garland Press, 2003. ISBN: 0815320515.

额外参考资料:
Additional References

van Holde, K. E., W. C. Johnson及P. S. Ho共同著作之《物理生物化学原理》 Upper Saddle River, NJ: Prentice Hall, 1998. ISBN: 0137204590.
van Holde = van Holde, K. E., W. C. Johnson, and P. S. Ho. Principles of Physical Biochemistry. Upper Saddle River, NJ: Prentice Hall, 1998. ISBN: 0137204590.

Eisenberg, D.,及D. Crothers共同著作之《应用于生命科学的物理化学》 Menlo Park, CA: Benjamin/Cummings, 1979. ISBN: 080532402X.
Eisenberg = Eisenberg, D., and D. Crothers. Physical Chemistry with Applications to the Life Sciences. Menlo Park, CA: Benjamin/Cummings, 1979. ISBN: 080532402X.

Kittel, C.及 H. Kroemer共同著作之《热物理》第二版 San Francisco CA: W. H. Freeman, 1980. ISBN: 0716710889
Kittel = Kittel, C., and H. Kroemer. Thermal Physics. 2nd ed. San Francisco CA: W. H. Freeman, 1980. ISBN: 0716710889.

课程单元 教科书
TEXT READINGS
额外参考资料
ADDITIONAL REFERENCES
L1 简介
Introduction

统计力学的目的
Purpose of Stat Mech

机率
Probability
Ch. 1 (Ex. 1.1-1.6)
L2 机率
Probability
Ch. 1, 2
L3 平衡状态
Equilibrium States
Ch. 2 (Through Ex. 2.2)
L4 平衡状态– 扩散之晶格模型
Equilibrium States – Lattice Model for Diffusion

橡胶弹性学
Rubber Elasticity
Ch. 2
L5 简介热力学守恒定律(第一定律,量化与第二定律)
Introduction to Conservation Laws (1st Law, Quantization, 2nd Law)
Ch. 3
L6 外延性质:波兹曼定律与熵(entropy)
Boltzmann's Law and Entropy as an Extensive Property

“熵”(entropy)增加的定律
Law of Increased Entropy
Ch. 6 (Through Ex. 6.2) Kittel, Ch. 2
L7 波兹曼定律与外延性质熵(entropy)
More Boltzmann's Law

分配函数
Partition Functions
Ch. 6
L8 模拟计算
Simulations


聚合酵素链锁反应
PCR
E1 随堂测验一
Quiz I
L9 热力学系统
Thermodynamic Systems

内含与外延性质
Intensive/Extensive Properties

能量与熵(Entropy)的基本方程式
Fundamental Equations for Energy and Entropy

热力学驱动力之定义(第一部分)热力学作用力
Definitions of Thermodynamic Driving Forces (Part 1) Thermodynamic Forces

齐次函数
Homogeneous Functions

平衡,温度与压力的定
Definition of Equilibrium, Temperature, Pressure
Ch. 7 (To Ex. 7.4)
L10 简介化学位能-热循环-热,功与能量之间关系的第一定律
Introduction to Chemical Potential - Thermo Cycles - First Law Relations between Heat, Work, Energy
Ch. 7
L11 可逆与不可逆程序
Reversible and Irreversible Processes
Ch. 7
L12 简介自由能
Introduction to Free Energy

赫姆荷兹自由能
Helmholtz Free energy
Ch. 8
L13
Enthalpy

吉布斯自由能
Gibbs Free Energy
Ch. 8 Kittel Problem, 9.4

van Holde, Ch. 2
L14 基本方程式与其自然变数
Fundamental Equations and their Natural Variables

热容
Heat Capacities

平衡温度
Equilibrium Temperature
Ch. 8
L15 热力学循环
Thermodynamic Cycles

卡若循环与不等性质
Carnot Cycle and Inequality

热引擎
Heat Engines

路径相依性
Path Dependence
Ch. 8 Kittel, Ch. 8
L16 莫尔偏微性质
Partial Molar Properties
Ch. 9
L17 莫尔偏微性质II
Partial Molar Properties II
Ch. 9 Eisenberg, Ch. 7
L18 计算机模拟
Simulations


蒙地卡罗法
Monte Carlo
E2 随堂测验二
Quiz II
L19 波兹曼分布定律
Boltzmann Distribution Law
Ch. 10
L20 分配函数
Partition Functions
Ch. 10
L21 从分配函数预测热力学性质
Prediction of Thermodynamic Properties from Partition Functions

系集
Ensembles
Ch. 10 Eisenberg, Ch. 14
L22 量子分布函数
Quantum Partition Function
Ch. 10, 11
L23 均分原理
Equipartition
Ch. 11
L24 均分原理 (续)
Equipartition (cont.)
Ch. 11
L25 化学平衡
Chemical Equlibria

列沙特勒原理 (Ex. 8, 蛋白质的应力变性)
Le Chatelier's Principle (Ex. 8, Pressure Denaturation of Proteins)

凡特何夫(van’t Hoff)原理
van't Hoff
Ch. 13 (To Ex. 13.18) van Holde, Ch. 3
L26 固-液-气平衡
Solid-liquid-gas Equilibrium
Ch. 14
L27 溶液与混合物
Solutions and Mixtures

高分子
Polymers
Ch. 15, 31
L28 溶解现象:渗透压
Solvation – Osmotic Pressure
Ch. 16
L29 溶解现象:蛋白质/巨分子在介面的吸附现象
Solvation – Protein/Macromolecule Adsorption at Interfaces
Ch. 16 van Holde, Ch. 2
L30 高分子链
Polymer Chain
Ch. 31
E3 随堂测验三
Quiz III
L31 高分子链 II
Polymer Chain II
Ch. 32
L32 高分子链 III
Polymer Chain III
Ch. 33
L33 协同性
Cooperativity
Ch. 26
L34 协同性 (续)
Cooperativity (cont.)
Ch. 28
L35 蛋白质摺叠现象
Protein Folding
van Holde, Ch. 2
L36 回顾
Review